Publications

Our scientific publications in high-quality journals reflect the quality of the innovative research in Entasis’ laboratories.

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Kohlhoff SA, Huband MD, and Hammerschlag MR

In vitro activity of AZD0914, a novel DNA gyrase inhibitor, against Chlamydia trachomatis and Chlamydia pneumoniae

Antimicrobial Agents and Chemotherapy (2014)

Huband MD, Bradford PA, Otterson LG, Basarab GS, Kutschke AC, Giacobbe RA, Patey SA, Alm RA, Johnstone MR, Potter ME, Miller PF, and Mueller JP

In vitro antibacterial activity of AZD0914: a new spiropyrimidinetrione DNA gyrase/topoisomerase inhibitor with potent activity against Gram-positive, fastidious Gram-negative, and atypical bacteria

Antimicrobial Agents and Chemotherapy (2015)

Brown DG, May-Dracka TL, Gagnon MM, and Tommasi R

Trends and exceptions of physical properties on antibacterial activity for Gram-positive and Gram-negative pathogens

Journal of Medicinal Chemistry (2014)

Basarab GS, Brassil P, Doig P, Galullo V, Haimes HB, Kern G, Kutschke A, McNulty J, Schuck VJ, Stone G, and Gowravaram M

Novel DNA gyrase inhibiting spiropyrimidinetriones with a benzisoxazole scaffold: SAR and in vivo characterization

Journal of Medicinal Chemistry (2014)