Our scientific publications in high-quality journals reflect the quality of the innovative research in Entasis’ laboratories.

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Waites KB, Crabb DM, Duffy LB, and Huband MD

In vitro Antibacterial activity of AZD0914 against human mycoplasmas and ureaplasmas

Antimicrobial Agents and Chemotherapy (2015)

Tommasi R, Brown DG, Walkup GK, Manchester JI, and Miller AA

ESKAPing the labyrinth of antibacterial discovery

Nature Reviews Drug Discovery (2015)

Zhou Y, Joubran C, Miller-Vedam L, Isabella V, Nayar A, Tentarelli S, and Miller A

Thinking outside the “bug”: a unique assay to measure intracellular drug penetration in Gram-negative bacteria

Analytical Chemistry (2015)

Isabella VM, Campbell AJ, Manchester J, Sylvester M, Nayar AS, Ferguson KE, Tommasi R, and Miller AA

Toward the rational design of carbapenem uptake in Pseudomonas aeruginosa

Chemistry & Biology (2015)

Alm RA, Lahiri SD, Kutschke A, Otterson LG, McLaughlin RE, Whiteaker JD, Lewis LA, Su X, Huband MD, Gardner H, and Mueller JP

Characterization of the novel DNA gyrase inhibitor AZD0914: low resistance potential and lack of cross-resistance in Neisseria gonorrhoeae

Antimicrobial Agents and Chemotherapy (2015)

Xiong H, Chen B, Durand-Réville TF, Joubran C, Alelyunas YW, Wu D, and Huynh H

Enantioselective synthesis and profiling of two novel diazabicyclooctanone β-lactamase inhibitors

ACS Medicinal Chemistry Letters (2014)

Campbell AJ, Lamb ML, and Joseph-McCarthy D

Ensemble-based docking using biased molecular dynamics

Journal of Chemical Information and Modeling (2014)