Our scientific publications in high-quality journals reflect the quality of the innovative research in Entasis’ laboratories.

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Perros M

A sustainable model for antibiotics

Science (2015)

Nayar A, Dougherty T, Ferguson K, Granger B, McWilliams L, Stacey C, Narita S, Tokuda H, Miller A, Brown D, McLeod S

Novel antibacterial targets and compounds revealed by a high throughput cell wall reporter assay

ASM Journal of Bacteriology (2015)

Penwell W, Giacobbe R, Gu R, Patey S, Shapiro S, Gao N, Thresher J, McLaughlin R, Huband M, De Jonge B, Ehmann D, Miller A

The molecular mechanisms of sulbactam antibacterial activity and resistance determinants in Acinetobacter baumannii

Antimicrobial Agents and Chemotherapy (2015)

Waites KB, Crabb DM, Duffy LB, Huband MD

In Vitro Antibacterial Activity of AZD0914 Against Human Mycoplasmas and Ureaplasmas

Antimicrobial Agents and Chemotherapy (2015)

Tommasi R, Brown DG, Walkup GK, Manchester JI, Miller AA

ESKAPing the Labyrinth of Antibacterial Discovery

Nature Reviews Drug Discovery (2015)

Zhou Y, Joubran C, Miller-Vedam L, Isabella V, Nayar A, Tentarelli S, Miller A

Thinking Outside the “Bug”:  A Unique Assay to Measure Intracellular Drug Penetration in Gram-Negative Bacteria

Analytical Chemistry (2015)

Isabella VM, Campbell AJ, Manchester J, Sylvester M, Nayar AS, Ferguson KE, Tommasi R, Miller A

Toward the Rational Design of Carbapenem Uptake in Pseudomonas aeruginosa.

Chemistry & Biology (Cell) (2015)

McLeod S, Fleming P, MacCormack K, McLaughlin R, Whiteaker J, Narita S, Moric M, Tokuda H, Miller A

Small-Molecule Inhibitors of Gram-Negative Lipoprotein Trafficking Discovered by Phenotypic Screening

ASM Journal of Bacteriology (2015)

Lahiri SD, Johnstone M, Ross PL, McLaughlin R, Olivier NB, Alm RA

Avibactam and class C ß-lactamases: mechanism of inhibition, conservation of binding pocket and implications for resistance

Antimicrobial Agents and Chemotherapy (2014)