Publications

McLeod S, Fleming P, MacCormack K, McLaughlin R, Whiteaker J, Narita S, Moric M, Tokuda H, Miller A

Small-Molecule Inhibitors of Gram-Negative Lipoprotein Trafficking Discovered by Phenotypic Screening

ASM Journal of Bacteriology (2015)

Lahiri SD, Johnstone M, Ross PL, McLaughlin R, Olivier NB, Alm RA

Avibactam and class C ß-lactamases: mechanism of inhibition, conservation of binding pocket and implications for resistance

Antimicrobial Agents and Chemotherapy (2014)

Alm R, Lahiri S, Kutschke A, Otterson L, McLaughlin R, Whiteaker J, Lewis L, Su X, Huband M, Gardner H, Mueller J

Characterization of the novel DNA gyrase inhibitor AZD0914: Low resistance potential and lack of cross-resistance in Neisseria gonorrhoeae

Antimicrobial Agents and Chemotherapy (2014)

Shapiro AB, Gu R, Gao N

Dimerization of isolated Pseudomonas aeruginosa lipopolysaccharide transporter component

ScienceDirect (2014)

Xiong H, Chen B, Durand-Réville T, Joubran C, Alelyunas Y, Wu D,Huynh H

Enantioselective Synthesis and Profiling of Two Novel Diazabicyclooctanone ß-Lactamase Inhibitors

ACS Publications (2014)

Campbell AJ, Lamb ML, Joseph-McCarthy D

Ensemble-Based Docking Using Biased Molecular Dynamics

Journal of Chemical Information and Modeling (2014)

Shapiro AB, Gao N, Gu R, Thresher J

Fluorescence anisotropy-based measurement of acylation rate constants for inhibitors of Penicillin-Binding Protein 2 (PBP2) transpeptidase of Pseudomonas aeruginosa

Analytical Biochemistry (2014)

Jacobsson S, Golparian D, Alm RA, Huband M, Mueller J, Skov Jensen J, Ohnishi M, Unemoa M

High in vitro activity of the novel spiropyrimidinetrione AZD0914, a DNA gyrase inhibitor, against multidrug resistant Neisseria gonorrhoeae isolates suggests a new effective option for oral treatment of gonorrhea

Antimicrobial Agents and Chemotherapy (2014)

Kohlhoff S, Huband M, Hammerschlag M

In vitro activity of AZD0914, a novel DNA gyrase inhibitor, against Chlamydia trachomatis and Chlamydia pneumoniae

Antimicrobial Agents and Chemotherapy (2014)

Huband M, Bradford P, Otterson L, Basarab G, Kutschke A, Giacobbe R, Patey S, Alm R, Johnstone M, Potter M, Miller P, Mueller J

In Vitro Antibacterial Activity of AZD0914: A New Spiropyrimidinetrione DNA Gyrase/Topoisomerase Inhibitor with Potent Activity against Gram-Positive, Fastidious Gram-Negative, and Atypical Bacteria

Antimicrobial Agents and Chemotherapy (2014)