Publications

O' Donnell J, Lawrence K, Vishwanathan K, Hosagrahara V, and Mueller JP

Single-dose pharmacokinetics, excretion, and metabolism of zoliflodacin, a novel spiropyrimidinetrione antibiotic, in healthy volunteers

Antimicrobial Agents and Chemotherapy (2018)

Cristillo AD, Bristow CC, Torrone E, Dillon J, Kirkcaldy RD, Dong H, Grad YH, Nicholas RA, Rice PA, Lawrence K, Oldach D, Shafer WM, Zhou P, Wi TE, Morris SR, and Klausner JD

Antimicrobial resistance in Neisseria gonorrhoeae: proceedings of the STAR sexually transmitted infection-clinical trial group programmatic meeting

Sexually Transmitted Diseases (2019)

Damião Gouveia AC, Unemo M, and Jensen JS

In vitro activity of zoliflodacin (ETX0914) against macrolide-resistant fluoroquinolone-resistant and antimicrobial-susceptible Mycoplasma genitalium strains

Journal of Antimicrobial Chemotherapy (2018)

Papp JR, Lawrence K, Sharpe S, Mueller J, and Kirkcaldy RD

In vitro growth of multidrug-resistant Neisseria gonorrhoeae isolates is inhibited by ETX0914, a novel spiropyrimidinetrione

International Journal of Antimicrobial Agents (2016)

Giacobbe RA, Huband MD, deJonge BLM, and Bradford PA

Effect of susceptibility testing conditions on the in vitro antibacterial activity of ETX0914

Diagnostic Microbiology and Infectious Disease (2017)

Guo J, Joubran C, Luzietti RA Jr, Basarab GS, Grimm SW, and Vishwanathan K

Absorption, distribution, metabolism and elimination of ¹⁴C-ETX0914, a novel inhibitor of bacterial type-II topoisomerases in rodents

Xenobiotica (2016)

Foerster S, Golparian D, Jacobsson S, Hathaway LJ, Low N, Shafer WM, Althaus CL, and Unemo M

Genetic resistance determinants, in vitro time-kill curve analysis and pharmacodynamic functions for the novel topoisomerase II inhibitor ETX0914 (AZD0914) in Neisseria gonorrhoeae

Frontiers in Microbiology (2015)

Su XH, Wang BX, Le WJ, Liu YR, Wan C, Li S, Alm RA, Mueller JP, and Rice PA

Multidrug resistant Neisseria gonorrhoeae from Nanjing are sensitive to killing by a novel DNA gyrase inhibitor, ETX0914 (AZD0914)

Antimicrobial Agents and Chemotherapy (2015)

Lancaster JW, Mahoney MV, Mandal S, and Lawrence KR

Update on treatment options for gonococcal infections

Pharmacotherapy (2015)

Biedenbach DJ, Huband MD, Hackel M, de Jonge BL, Sahm DF, and Bradford PA

In vitro activity of AZD0914, a novel bacterial DNA gyrase/topoisomerase IV inhibitor, against clinically relevant Gram-positive and fastidious Gram-negative pathogens

Antimicrobial Agents and Chemotherapy (2015)