Our scientific publications in high-quality journals reflect the quality of the innovative research in Entasis’ laboratories.

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Jacobsson S, Golparian D, Oxelbark J, Alirol FF, Gustafsson TN, Brown D, Louie A, Drusano G and Unemo M

Pharmacodynamic evaluation of dosing, bacterial kill, and resistance suppression for zoliflodacin against Neisseria gonorrhoeae in a dynamic hollow fiber infection model

Frontiers in Pharmacology (2021)

Le W, Su X, Lou X, Li X, Gong X, Wang B, Genco CA, Mueller JP and Rice PA

Susceptibility trends of zoliflodacin against multidrug-resistant Neisseria gonorrhoeae clinical isolates in Nanjing, China (2014-2018)

Antimicrobial Agents and Chemotherapy (2021)

Theuretzbacher U, Barbee L, Connolly K, Drusano G, Fernandes P, Hook E, Jerse A, O'Donnell J, Unemo M, Van Bambeke F, VanScoy B, Warn P, Werth BJ, Franceschi F, and Alirol E

Pharmacokinetic/pharmacodynamic considerations for new and current therapeutic drugs for uncomplicated gonorrhoea – challenges and opportunities

Clinical Microbiology and Infection (2020)

Miller AA, Traczewski MM, Huband MD, Bradford PA, Mueller JP

Determination of MIC quality control ranges for the novel gyrase inhibitor, zoliflodacin

Journal of Clinical Microbiology (2019)

Taylor SN, Marrazzo J, Batteiger BE, Hook EW, Seña AC, Long J, Wierzbicki MR, Kwak H, Johnson SM, Lawrence K, and Mueller J

Single-dose zoliflodacin (ETX0914) for treatment of urogenital gonorrhea

New England Journal of Medicine (2018)

O' Donnell J, Lawrence K, Vishwanathan K, Hosagrahara V, and Mueller JP

Single-dose pharmacokinetics, excretion, and metabolism of zoliflodacin, a novel spiropyrimidinetrione antibiotic, in healthy volunteers

Antimicrobial Agents and Chemotherapy (2018)

Cristillo AD, Bristow CC, Torrone E, Dillon J, Kirkcaldy RD, Dong H, Grad YH, Nicholas RA, Rice PA, Lawrence K, Oldach D, Shafer WM, Zhou P, Wi TE, Morris SR, and Klausner JD

Antimicrobial resistance in Neisseria gonorrhoeae: proceedings of the STAR sexually transmitted infection-clinical trial group programmatic meeting

Sexually Transmitted Diseases (2019)

Papp JR, Lawrence K, Sharpe S, Mueller J, and Kirkcaldy RD

In vitro growth of multidrug-resistant Neisseria gonorrhoeae isolates is inhibited by ETX0914, a novel spiropyrimidinetrione

International Journal of Antimicrobial Agents (2016)