Presentations by Event

Discovery of a Novel Series of Penicillin-binding Protein 3 Inhibitors to Treat Pseudomonas aeruginosa Infections: Rational Design of Biochemical Potency and Bacterial Permeation

Thomas Durand-Reville

Scientific Overview of Entasis Pipeline

Ruben Tommasi, ASM Microbe 2019

Novel Therapies Targeting Drug-Resistant Gonorrhea

John Mueller, ASM Microbe 2019

Program(s): zoliflodacin (etx0914)

The Novel β-lactamase Inhibitor ETX2514 Restores Sulbactam Activity against Recent, Globally Diverse Clinical Isolates of Acinetobacter baumannii calcoaceticus Complex Isolates

Sarah McLeod, ASM Microbe 2019

Program(s): etx2514

The Novel β-lactamase Inhibitor ETX1317 Restores the Activity of Cefpodoxime Against Drug-Resistant Enterobacteriaceae

Sarah McLeod, ASM Microbe 2019

Program(s): etx0282

Cefpodoxime-ETX1317 Susceptibility is Unaffected by Ceftazidime-Avibactam Resistance Mutations V240G, D179Y and D179Y/T243M in KPC-3 b-Lactamase

Adam Shapiro, ASM Microbe 2019

Program(s): etx0282

Pharmacokinetics/Pharmacodynamics and Phase 3 Dose Projection For the Novel β lactamase Inhibitor ETX2514 in Combination with Sulbactam Against Acinetobacter baumannii calcoaceticus Complex (ABC)

John O'Donnell, ASM Microbe 2019

Program(s): etx2514

Pharmacokinetics/Pharmacodynamics and Phase 3 Dose Projection For the Novel β-lactamase Inhibitor ETX2514 in Combination with Sulbactam Against Acinetobacter baumannii-calcoaceticusComplex (ABC)

John O'Donnell, ASM Microbe 2019

Program(s): etx2514

Population Pharmacokinetic and Pharmacokinetic-Pharmacodynamic Target Attainment Analyses of ETX2514SUL to Support Dosing Regimens in Patients with Varying Renal Function

N.J. Onufrak (ICPD), ECCMID 2019

Program(s): etx2514

Efficacy of Cefpodoxime proxetil and ETX0282 in a murine UTI model with E. coli and K. pneumoniae

W.J. Weiss (UNTHSC), ECCMID 2019

Program(s): etx0282

The Susceptibility of Sulbactam/ETX2514 and Comparators to Global Isolates of Acinetobacter baumannii

Harald Seifert (University of Cologne), ECCMID 2019

Program(s): etx2514

Restoration of Sulbactam Activity by the Novel β-lactamase Inhibitor ETX2514 Against Recent Global Clinical Isolates of Acinetobacter baumanniicalcoaceticusComplex Isolates

Sarah McLeod, ECCMID 2019

Program(s): etx2514

A Double-blind, Randomized, Placebo-controlled Study to Evaluate the Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of Hospitalized Adults with Complicated Urinary Tract Infections, Including Acute Pyelonephritis

Suba Srinivasan, ECCMID 2019

Program(s): etx2514

Discovery of a novel series of Penicillin-Binding Protein 3 inhibitors as monotherapy for Pseudomonas aeruginosa infections: Rational design of biochemical potency and bacterial permeation

Thomas Durand-Reville, ECCMID 2019

The Novel β-lactamase Inhibitor ETX1317 Effectively Restores the Activity of Cefpodoxime Against Recent Global EnterobacteriaceaeIsolates from Urinary Tract Infections

Sarah McLeod, ECCMID 2019

Program(s): etx0282