Title: Senior Scientist/Principal Scientist - Medicinal Chemistry
Location: Waltham, MA
About Entasis Therapeutics
Entasis is developing a portfolio of innovative product candidates to treat serious Gram-negative multi-drug resistant infections. Entasis’ anti-infective discovery platform has produced a pipeline of meaningfully differentiated programs which target serious bacterial infections.
Key Responsibilities:
- Synthesize, isolate and characterize novel bioactive molecules for Entasis discovery projects
- Contribute to medicinal chemistry plans in a very impactful manner (including analog synthesis, compound design and synthetic route identification)
- Strong presence in the lab with high level of productivity
- Demonstrate teamwork and promote an open and innovative culture within a cross discipline environment
- Work in accordance to local safety requirements and in compliance with all company policies
Minimum Qualifications:
- PhD in Organic Chemistry with 0-5 years of research experience
- In-depth knowledge of modern organic chemistry and synthesis techniques and tools with demonstrated impact on research projects
- Proven track record of solving complex synthetic challenges and high level of productivity
- Ability to successfully design and implement novel chemistry routes
- Strong publication record in peer-reviewed journals and/or evidence of sustained contributions to the field
- Team player with a positive and proactive attitude with respect to out-of-box thinking, multitasking and willingness to learn and challenge status quo
- Excellent writing and verbal communication; strong computer, scientific, and organizational skills
Preferred Qualifications:
- Experience in medicinal chemistry, preferably in a biopharmaceutical setting
- Experience working with external CROs, including project planning and prioritization of work, as well as academic/industrial collaborations