Our Science

Publications 2017

Our scientific publications in high-quality journals reflect the quality of the innovative research in Entasis’ laboratories.

Adam B. Shapiro, Ning Gao, Haris Jahić, Nicole M. Carter, April Chen, and Alita A. Miller.
Reversibility of Covalent, Broad-Spectrum Serine β-Lactamase Inhibition by the Diazabicyclooctenone ETX2514
ACS Infectious Diseases (2017)

Shapiro, Adam B.
Investigation of β-lactam antibacterial drugs, β-lactamases, and penicillin-binding proteins with fluorescence polarization and anisotropy: a review
IOP Science (2017)

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Durand-Réville T, et al
ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii
Nature Microbiology (2017)

Iyer R, Sylvester M, Velez-Vega C, Tommasi R, Durand-Réville T, Miller A*
Whole-Cell-Based Assay To Evaluate Structure Permeation Relationships for Carbapenem Passage through the Pseudomonas aeruginosa Porin OprD
ACS Infectious Diseases (2017)



“Our scientific approach and expertise, coupled with Entasis’ strong pipeline of programs, really make us stand out in the field of antibacterial drug discovery and development.”

— Satenig Guler, Senior Scientist