Our scientific publications in high-quality journals reflect the quality of the innovative research in Entasis’ laboratories.

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Zhou Y, Joubran C, Miller-Vedam L, Isabella V, Nayar A, Tentarelli S, Miller A

Thinking Outside the “Bug”:  A Unique Assay to Measure Intracellular Drug Penetration in Gram-Negative Bacteria

Analytical Chemistry (2015)

Isabella VM, Campbell AJ, Manchester J, Sylvester M, Nayar AS, Ferguson KE, Tommasi R, Miller A

Toward the Rational Design of Carbapenem Uptake in Pseudomonas aeruginosa.

Chemistry & Biology (Cell) (2015)

McLeod S, Fleming P, MacCormack K, McLaughlin R, Whiteaker J, Narita S, Moric M, Tokuda H, Miller A

Small-Molecule Inhibitors of Gram-Negative Lipoprotein Trafficking Discovered by Phenotypic Screening

ASM Journal of Bacteriology (2015)

Lahiri SD, Johnstone M, Ross PL, McLaughlin R, Olivier NB, Alm RA

Avibactam and class C ß-lactamases: mechanism of inhibition, conservation of binding pocket and implications for resistance

Antimicrobial Agents and Chemotherapy (2014)

Alm R, Lahiri S, Kutschke A, Otterson L, McLaughlin R, Whiteaker J, Lewis L, Su X, Huband M, Gardner H, Mueller J

Characterization of the novel DNA gyrase inhibitor AZD0914: Low resistance potential and lack of cross-resistance in Neisseria gonorrhoeae

Antimicrobial Agents and Chemotherapy (2014)

Xiong H, Chen B, Durand-Réville T, Joubran C, Alelyunas Y, Wu D,Huynh H

Enantioselective Synthesis and Profiling of Two Novel Diazabicyclooctanone ß-Lactamase Inhibitors

ACS Publications (2014)

Campbell AJ, Lamb ML, Joseph-McCarthy D

Ensemble-Based Docking Using Biased Molecular Dynamics

Journal of Chemical Information and Modeling (2014)