Publications

Our scientific publications in high-quality journals reflect the quality of the innovative research in Entasis’ laboratories.

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Stephanie N. Taylor, M.D., Jeanne Marrazzo, M.D., M.P.H., Byron E. Batteiger, M.D., Edward W. Hook, III, M.D., Arlene C. Seña, M.D., M.P.H., Jill Long, M.D., M.P.H., Michael R. Wierzbicki, Ph.D., Hannah Kwak, M.H.S., Shacondra M. Johnson, B.S.P.H., Kenneth Lawrence, Pharm.D., and John Mueller, Ph.D.

Single-Dose Zoliflodacin (ETX0914) for Treatment of Urogenital Gonorrhea

New England Journal of Medicine

John O' Donnell, Ken Lawrence, Karthick Vishwanathan, Vinayak Hosagrahara, John P. Mueller

Single-dose Pharmacokinetics, Excretion, and Metabolism of Zoliflodacin, a Novel Spiropyrimidinetrione Antibiotic, in Healthy Volunteers

AAC Accepted Manuscript posted online October 29, 2018

Anthony D. Cristillo, PhD, MS; Claire C. Bristow, PhD, MPH, MSc; Elizabeth Torrone, MSPH, PhD; Jo-Anne Dillon, MSc, PhD, FCAHS, FRSC; Robert D. Kirkcaldy, MD, MPH , Huan Dong, MS; Yonatan H. Grad, MD, PhD; Robert A. Nicholas, PhD; Peter A. Rice, MD; Kenneth Lawrence, PharmD; David Oldach, MD, FIDSA; William Maurice Shafer, PhD; Pei Zhou, PhD; Teodora E. Wi, MD; Sheldon R. Morris, MD, MPH; and Jeffrey D. Klausner, MD, MPH

Antimicrobial Resistance in Neisseria gonorrhoeae: Proceedings of the STAR Sexually Transmitted Infection-Clinical Trial Group Programmatic Meeting

Journal of Sexually Transmitted Diseases

Rodvold KA, Gotfried MH, Isaacs RD, O'Donnell JP, Stone E

Plasma and Intrapulmonary Concentrations of ETX2514 and Sulbactam following Intravenous Administration of ETX2514SUL to Healthy Adult Subjects

AAC Accepted Manuscript Posted Online 20 August 2018

Ruben Tommasi, Ram Iyer, Alita Miller

Antibacterial Drug Discovery: Some Assembly Required

National Center for Biotechnology Information

Ram Iyer, Samir Moussa, Thomas Durand-Réville, Ruben Tommasi, Alita Miller

Acinetobacter baumannii OmpA Is a Selective Antibiotic Permeant Porin

National Center for Biotechnology Information

Damião Gouveia, A.C., Unemo, M. and Jensen, J.S.

In vitro activity of zoliflodacin (ETX0914) against macrolide-resistant fluoroquinolone-resistant and antimicrobial-susceptible Mycoplasma genitalium strains

J Antimicrobial Chemotherapy doi:10.1093/jac/dky022 (2018)

S. McLeod, A. Shapiro, S. Moussa, M. Johnstone, R. McLaughlin, B. de Jonge and A. Miller

Frequency and Mechanism of Spontaneous Resistance to Sulbactam Combined with the Novel β-Lactamase Inhibitor ETX2514 in Clinical Isolates of Acinetobacter baumannii

Antimicrob. Agents Chemother. February 2018 vol. 62 no. 2 e01576-17

Adam B. Shapiro, Ning Gao, Haris Jahić, Nicole M. Carter, April Chen, and Alita A. Miller.

Reversibility of Covalent, Broad-Spectrum Serine β-Lactamase Inhibition by the Diazabicyclooctenone ETX2514

ACS Infectious Diseases (2017)