About Us

Focused on next generation antibacterial therapeutics

Our Story

Entasis Therapeutics was established in 2015 with start-up funding from AstraZeneca, and all rights to AstraZeneca’s industry-leading discovery and early development small-molecule anti-infectives portfolio. Since our startup funding from Astrazeneca, we have raised another $81.9 million in Series B and B-1 financings from a strong syndicate of investors, including Clarus, Frazier Healthcare Partners, Novo A/S, Pivotal bioVenture Partners, TPG Biotech, Sofinnova Ventures, and Eventide Funds, to advance our pipeline of breakthrough anti-infective products.

Our Approach

With our unique pathogen-targeted approach, we have developed a robust clinical and pre-clinical pipeline of first- and best-in-class medicines. This includes small-molecule programs to treat serious multidrug-resistant Gram-negative infections, including Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacteriaceae, and a single dose oral therapy for susceptible and drug-resistant Neisseria gonorrhoeae.

Our Team

Our leaders and scientists have deep knowledge, and a track record of discovery and development of innovative anti-infectives from biotech, academia and big pharma. When you work with us, you invest in the energy and determination of a small biotech, combined with the expertise and portfolio of a global pharmaceutical company.

Our Mission

We are all on the verge of a serious public health crisis. As antibacterial resistance to antibiotics grows, it becomes increasingly difficult to manage a wide range of infections, which often results in poor outcomes for patients and escalating healthcare costs.

We believe in meaningful change.

We are committed to keeping bacterial resistance at bay. And we will never become complacent with substandard medications. Instead, we will continue to create value with new therapies that are precise, effective and safe.

We strive to restore health to people affected by serious infectious disease caused by drug-resistant Gram-negative bacteria–with exactly the right drug in exactly the right way.

This is how we will make the biggest impact.